TY  - GEN
AU  - Jane-wit,Dan
AU  - Surovtseva,Yulia V
AU  - Qin,Lingfeng
AU  - Li,Guangxin
AU  - Liu,Rebecca
AU  - Clark,Pamela
AU  - Manes,Thomas D
AU  - Wang,Chen
AU  - Kashgarian,Michael
AU  - Kirkiles-Smith,Nancy C
AU  - Tellides,George
AU  - Pober,Jordan S
TI  - Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes
SN  - 1091-6490
PY  - 2015///1117
KW  - Animals
KW  - Baculoviral IAP Repeat-Containing 3 Protein
KW  - Clathrin
KW  - metabolism
KW  - Complement Membrane Attack Complex
KW  - Coronary Vessels
KW  - drug effects
KW  - Endocytosis
KW  - Endosomes
KW  - Enzyme Stability
KW  - Flow Cytometry
KW  - Human Umbilical Vein Endothelial Cells
KW  - Humans
KW  - Hydrazones
KW  - pharmacology
KW  - Inhibitor of Apoptosis Proteins
KW  - Mice, SCID
KW  - NF-kappa B
KW  - Protein Biosynthesis
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins c-akt
KW  - RNA, Small Interfering
KW  - Secretory Vesicles
KW  - Signal Transduction
KW  - TNF Receptor-Associated Factor 3
KW  - Ubiquitin-Protein Ligases
KW  - rab5 GTP-Binding Proteins
KW  - NF-kappaB-Inducing Kinase
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1073/pnas.1503535112
ER  -