Jane-wit, Dan <br/><br/>
Complement membrane attack complexes activate noncanonical NF-κB by forming an Akt+ NIK+ signalosome on Rab5+ endosomes.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Aug 2015 
 - 9686-91 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1091-6490 
<br/><br/><label>Standard No.: </label>10.1073/pnas.1503535112  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Baculoviral IAP Repeat-Containing 3 Protein<br/>Clathrin--metabolism<br/>Complement Membrane Attack Complex--metabolism<br/>Coronary Vessels--drug effects<br/>Endocytosis--drug effects<br/>Endosomes--drug effects<br/>Enzyme Stability--drug effects<br/>Flow Cytometry<br/>Human Umbilical Vein Endothelial Cells--drug effects<br/>Humans<br/>Hydrazones--pharmacology<br/>Inhibitor of Apoptosis Proteins--metabolism<br/>Mice, SCID<br/>NF-kappa B--metabolism<br/>Protein Biosynthesis--drug effects<br/>Protein Serine-Threonine Kinases--metabolism<br/>Proto-Oncogene Proteins c-akt--metabolism<br/>RNA, Small Interfering--metabolism<br/>Secretory Vesicles--drug effects<br/>Signal Transduction--drug effects<br/>TNF Receptor-Associated Factor 3--metabolism<br/>Ubiquitin-Protein Ligases--metabolism<br/>rab5 GTP-Binding Proteins--metabolism<br/>NF-kappaB-Inducing Kinase