TY - GEN AU - Hanafusa,Hiroshi AU - Kedashiro,Shin AU - Tezuka,Motohiro AU - Funatsu,Motoki AU - Usami,Satoshi AU - Toyoshima,Fumiko AU - Matsumoto,Kunihiro TI - PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2 SN - 1476-4679 PY - 2015///1022 KW - Amino Acid Motifs KW - Animals KW - Binding Sites KW - CDC2 Protein Kinase KW - COS Cells KW - Cell Cycle Proteins KW - genetics KW - Centrosome KW - enzymology KW - Chlorocebus aethiops KW - Cyclin-Dependent Kinases KW - metabolism KW - Enzyme Activation KW - HEK293 Cells KW - HeLa Cells KW - Humans KW - Intracellular Signaling Peptides and Proteins KW - Microtubules KW - Mitosis KW - Mutation KW - Nerve Tissue Proteins KW - Phosphorylation KW - Protein Binding KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - RNA Interference KW - Serine KW - Signal Transduction KW - Spindle Apparatus KW - Time Factors KW - Transfection KW - Tubulin KW - Polo-Like Kinase 1 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/ncb3204 ER -