PLK1-dependent activation of LRRK1 regulates spindle orientation by phosphorylating CDK5RAP2. [electronic resource]
- Nature cell biology Aug 2015
- 1024-35 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1476-4679
10.1038/ncb3204 doi
Amino Acid Motifs Animals Binding Sites CDC2 Protein Kinase COS Cells Cell Cycle Proteins--genetics Centrosome--enzymology Chlorocebus aethiops Cyclin-Dependent Kinases--metabolism Enzyme Activation HEK293 Cells HeLa Cells Humans Intracellular Signaling Peptides and Proteins--genetics Microtubules--enzymology Mitosis Mutation Nerve Tissue Proteins--genetics Phosphorylation Protein Binding Protein Serine-Threonine Kinases--genetics Proto-Oncogene Proteins--genetics RNA Interference Serine Signal Transduction Spindle Apparatus--enzymology Time Factors Transfection Tubulin--metabolism Polo-Like Kinase 1