TY - GEN AU - Iwaoka,Emiko AU - Wang,Shenglan AU - Matsuyoshi,Nobuyuki AU - Kogure,Yoko AU - Aoki,Shunji AU - Yamamoto,Satoshi AU - Noguchi,Koichi AU - Dai,Yi TI - Evodiamine suppresses capsaicin-induced thermal hyperalgesia through activation and subsequent desensitization of the transient receptor potential V1 channels SN - 1861-0293 PY - 2016///0726 KW - Alkaloids KW - pharmacology KW - Analgesics KW - Animals KW - Calcium KW - metabolism KW - Calcium Channels KW - Capsaicin KW - analogs & derivatives KW - Dose-Response Relationship, Drug KW - Evodia KW - chemistry KW - Ganglia, Spinal KW - physiology KW - HEK293 Cells KW - Hot Temperature KW - Humans KW - Hyperalgesia KW - chemically induced KW - Male KW - Medicine, Chinese Traditional KW - Nerve Tissue Proteins KW - Neurons KW - drug effects KW - Patch-Clamp Techniques KW - Plant Extracts KW - Quinazolines KW - Quinolines KW - Rats KW - Rats, Sprague-Dawley KW - TRPA1 Cation Channel KW - TRPV Cation Channels KW - agonists KW - Transient Receptor Potential Channels N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s11418-015-0929-1 ER -