TY  - GEN
AU  - Korkola,James E
AU  - Collisson,Eric A
AU  - Heiser,Laura
AU  - Oates,Chris
AU  - Bayani,Nora
AU  - Itani,Sleiman
AU  - Esch,Amanda
AU  - Thompson,Wallace
AU  - Griffith,Obi L
AU  - Wang,Nicholas J
AU  - Kuo,Wen-Lin
AU  - Cooper,Brian
AU  - Billig,Jessica
AU  - Ziyad,Safiyyah
AU  - Hung,Jenny L
AU  - Jakkula,Lakshmi
AU  - Feiler,Heidi
AU  - Lu,Yiling
AU  - Mills,Gordon B
AU  - Spellman,Paul T
AU  - Tomlin,Claire
AU  - Mukherjee,Sach
AU  - Gray,Joe W
TI  - Decoupling of the PI3K Pathway via Mutation Necessitates Combinatorial Treatment in HER2+ Breast Cancer
SN  - 1932-6203
PY  - 2016///0427
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - Diamines
KW  - Drug Resistance, Neoplasm
KW  - genetics
KW  - Epithelial Cells
KW  - drug effects
KW  - Female
KW  - Gene Expression Profiling
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Lapatinib
KW  - Mammary Glands, Human
KW  - Mutation
KW  - Oxadiazoles
KW  - Phosphatidylinositol 3-Kinases
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - antagonists & inhibitors
KW  - Pyrazoles
KW  - Quinazolines
KW  - Receptor, ErbB-2
KW  - Ribosomal Protein S6
KW  - Signal Transduction
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pone.0133219
ER  -