Lin, An-Ping

D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. [electronic resource] - Nature communications Jul 2015 - 7768 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

2041-1723

10.1038/ncomms8768 doi


Alcohol Oxidoreductases--genetics
Blotting, Western
Cell Line, Tumor
DNA Methylation--genetics
Dioxygenases--metabolism
Epigenesis, Genetic
Gene Expression Regulation, Neoplastic
HEK293 Cells
Histones--metabolism
Humans
Hydroxylation--genetics
Hypoxia-Inducible Factor 1, alpha Subunit--metabolism
Isocitrate Dehydrogenase--genetics
Ketoglutaric Acids--metabolism
Lymphoma, Large B-Cell, Diffuse--genetics
Methylation
Real-Time Polymerase Chain Reaction