TY - GEN AU - Li,Wei AU - Zhang,Yu AU - Xing,Cuiyan AU - Zhang,Mengyuan TI - Tanshinone IIA represses inflammatory response and reduces radiculopathic pain by inhibiting IRAK-1 and NF-κB/p38/JNK signaling SN - 1878-1705 PY - 2016///0629 KW - Abietanes KW - pharmacology KW - Analgesics KW - Animals KW - Anti-Inflammatory Agents, Non-Steroidal KW - Cell Survival KW - drug effects KW - Cells, Cultured KW - Cyclooxygenase 2 KW - genetics KW - Drugs, Chinese Herbal KW - Female KW - Humans KW - Interleukin-1 Receptor-Associated Kinases KW - metabolism KW - Interleukin-1beta KW - Intervertebral Disc KW - cytology KW - Intervertebral Disc Degeneration KW - drug therapy KW - Intervertebral Disc Displacement KW - JNK Mitogen-Activated Protein Kinases KW - Matrix Metalloproteinase 1 KW - Matrix Metalloproteinase 13 KW - NF-kappa B KW - Nitric Oxide Synthase Type II KW - Pain KW - Rats, Sprague-Dawley KW - p38 Mitogen-Activated Protein Kinases N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.intimp.2015.06.032 ER -