Dorresteijn, Bram <br/><br/>
Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo.  [electronic resource] 

 -  The FEBS journal  Sep 2015 
 - 3618-31 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1742-4658 
<br/><br/><label>Standard No.: </label>10.1111/febs.13367  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alzheimer Disease--genetics<br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Amyloid beta-Protein Precursor--genetics<br/>Animals<br/>Aspartic Acid Endopeptidases--antagonists & inhibitors<br/>Camelids, New World--immunology<br/>Cell Line<br/>Disease Models, Animal<br/>Disease Progression<br/>Female<br/>Humans<br/>Immunoglobulin Fragments--administration & dosage<br/>Immunoglobulin Heavy Chains--administration & dosage<br/>In Vitro Techniques<br/>Mice<br/>Mice, Transgenic<br/>Recombinant Proteins--genetics<br/>Vaccination