TY - GEN AU - Moilanen,Anu-Maarit AU - Riikonen,Reetta AU - Oksala,Riikka AU - Ravanti,Laura AU - Aho,Eija AU - Wohlfahrt,Gerd AU - Nykänen,Pirjo S AU - Törmäkangas,Olli P AU - Palvimo,Jorma J AU - Kallio,Pekka J TI - Discovery of ODM-201, a new-generation androgen receptor inhibitor targeting resistance mechanisms to androgen signaling-directed prostate cancer therapies SN - 2045-2322 PY - 2016///0804 KW - Androgen Receptor Antagonists KW - pharmacology KW - Androgens KW - physiology KW - Animals KW - Antineoplastic Agents KW - pharmacokinetics KW - Cell Line, Tumor KW - Drug Resistance, Neoplasm KW - HEK293 Cells KW - Humans KW - Male KW - Mice, Inbred BALB C KW - Mice, Nude KW - Prostatic Neoplasms KW - drug therapy KW - Pyrazoles KW - Receptors, Androgen KW - metabolism KW - Signal Transduction KW - Tumor Burden KW - drug effects KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep12007 ER -