Liu, Zhao

Phenformin Induces Cell Cycle Change, Apoptosis, and Mesenchymal-Epithelial Transition and Regulates the AMPK/mTOR/p70s6k and MAPK/ERK Pathways in Breast Cancer Cells. [electronic resource] - PloS one 2015 - e0131207 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1932-6203

10.1371/journal.pone.0131207 doi


AMP-Activated Protein Kinases--metabolism
Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Breast Neoplasms--metabolism
Cell Cycle--drug effects
Epithelial-Mesenchymal Transition--drug effects
Female
Humans
Hypoglycemic Agents--pharmacology
MAP Kinase Signaling System--drug effects
MCF-7 Cells
Mice
Mice, Inbred BALB C
Mice, Nude
Phenformin--pharmacology
Ribosomal Protein S6 Kinases, 70-kDa--metabolism
TOR Serine-Threonine Kinases--metabolism
Tumor Cells, Cultured
Xenograft Model Antitumor Assays