TY  - GEN
AU  - Tedeschi,Philip M
AU  - Vazquez,Alexei
AU  - Kerrigan,John E
AU  - Bertino,Joseph R
TI  - Mitochondrial Methylenetetrahydrofolate Dehydrogenase (MTHFD2) Overexpression Is Associated with Tumor Cell Proliferation and Is a Novel Target for Drug Development
SN  - 1557-3125
PY  - 2016///0706
KW  - Aminohydrolases
KW  - biosynthesis
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Cell Proliferation
KW  - drug effects
KW  - Drug Design
KW  - Humans
KW  - Methylenetetrahydrofolate Dehydrogenase (NADP)
KW  - Mice
KW  - Mitochondria
KW  - enzymology
KW  - Models, Molecular
KW  - Molecular Targeted Therapy
KW  - Multienzyme Complexes
KW  - Neoplasms
KW  - drug therapy
KW  - Protein Conformation
KW  - Protein Folding
KW  - Structure-Activity Relationship
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1158/1541-7786.MCR-15-0117
ER  -