TY  - GEN
AU  - Xu,Xing
AU  - Xu,Xin
AU  - Liu,Peng
AU  - Zhu,Zhi-yuan
AU  - Chen,Jing
AU  - Fu,Hai-an
AU  - Chen,Li-li
AU  - Hu,Li-hong
AU  - Shen,Xu
TI  - Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor α (FXRα) in Stabilizing the Homodimerization of the Receptor
SN  - 1083-351X
PY  - 2015///1105
KW  - ATP Binding Cassette Transporter, Subfamily B, Member 11
KW  - ATP-Binding Cassette Transporters
KW  - antagonists & inhibitors
KW  - Animals
KW  - Benzamides
KW  - chemistry
KW  - Crystallography, X-Ray
KW  - Gene Expression Regulation
KW  - Glucose-6-Phosphatase
KW  - Hep G2 Cells
KW  - Hepatocytes
KW  - cytology
KW  - Humans
KW  - Isoxazoles
KW  - Male
KW  - Mice
KW  - Mice, Knockout
KW  - Molecular Docking Simulation
KW  - Mutation
KW  - Phosphoenolpyruvate Carboxykinase (ATP)
KW  - Primary Cell Culture
KW  - Protein Isoforms
KW  - agonists
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Receptors, Leptin
KW  - deficiency
KW  - Recombinant Proteins
KW  - genetics
KW  - Retinoid X Receptors
KW  - Signal Transduction
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1074/jbc.M114.630475
ER  -