TY - GEN AU - Ellis,Peter M AU - Leighl,Natasha B AU - Hirsh,Vera AU - Reaume,M Neil AU - Blais,Normand AU - Wierzbicki,Rafal AU - Sadrolhefazi,Behbood AU - Gu,Yu AU - Liu,Dan AU - Pilz,Korinna AU - Chu,Quincy TI - A Randomized, Open-Label Phase II Trial of Volasertib as Monotherapy and in Combination With Standard-Dose Pemetrexed Compared With Pemetrexed Monotherapy in Second-Line Treatment for Non-Small-Cell Lung Cancer SN - 1938-0690 PY - 2016///0815 KW - Adult KW - Aged KW - Aged, 80 and over KW - Carcinoma, Non-Small-Cell Lung KW - drug therapy KW - Cell Cycle Proteins KW - antagonists & inhibitors KW - Drug Dosage Calculations KW - Drug Interactions KW - Drug Resistance, Neoplasm KW - Drug Therapy, Combination KW - Fatigue KW - etiology KW - Female KW - Humans KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Nausea KW - Pemetrexed KW - administration & dosage KW - Platinum Compounds KW - therapeutic use KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins KW - Pteridines KW - Survival Analysis KW - Polo-Like Kinase 1 N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.cllc.2015.05.010 ER -