Boucle, Sebastien <br/><br/>
Design, synthesis and evaluation of novel anti-HCV molecules that deliver intracellularly three highly potent NS5A inhibitors.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Sep 2015 
 - 3711-5 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2015.06.031  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antiviral Agents--administration & dosage<br/>Carbamates<br/>Cell Line--drug effects<br/>Chemistry Techniques, Synthetic<br/>Chlorocebus aethiops<br/>Drug Design<br/>Drug Evaluation, Preclinical--methods<br/>Hepacivirus--drug effects<br/>Humans<br/>Imidazoles--pharmacology<br/>Molecular Targeted Therapy<br/>Mutation<br/>Pyrrolidines<br/>Structure-Activity Relationship<br/>Valine--analogs & derivatives<br/>Vero Cells--drug effects<br/>Viral Nonstructural Proteins--antagonists & inhibitors<br/>Virus Replication--drug effects