S P, Nipin <br/><br/>
The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts.  [electronic resource] 

 -  BMC cancer  Jun 2015 
 - 474 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1471-2407 
<br/><br/><label>Standard No.: </label>10.1186/s12885-015-1445-0  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Combined Chemotherapy Protocols--administration & dosage<br/>Breast Neoplasms--drug therapy<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Dimethyl Sulfoxide--administration & dosage<br/>Estrogen Receptor alpha--genetics<br/>Female<br/>Humans<br/>Janus Kinase 2--antagonists & inhibitors<br/>Neoplasm Metastasis<br/>Receptors, Somatomedin--antagonists & inhibitors<br/>STAT5 Transcription Factor--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>Sulfones--administration & dosage<br/>Tamoxifen--administration & dosage<br/>Xenograft Model Antitumor Assays