TRAIL-Based High Throughput Screening Reveals a Link between TRAIL-Mediated Apoptosis and Glutathione Reductase, a Key Component of Oxidative Stress Response. [electronic resource]
- PloS one 2015
- e0129566 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1932-6203
10.1371/journal.pone.0129566 doi
Animals Antineoplastic Agents--pharmacology Apoptosis--drug effects Cell Line, Tumor Dose-Response Relationship, Drug Doxorubicin--pharmacology Drug Discovery Glutathione--metabolism Glutathione Reductase--antagonists & inhibitors High-Throughput Screening Assays Humans Mice Oxidative Stress Reactive Oxygen Species Small Molecule Libraries TNF-Related Apoptosis-Inducing Ligand--metabolism