TY - GEN AU - Keohane,Clodagh AU - Kordasti,Shahram AU - Seidl,Thomas AU - Perez Abellan,Pilar AU - Thomas,Nicholas S B AU - Harrison,Claire N AU - McLornan,Donal P AU - Mufti,Ghulam J TI - JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells SN - 1365-2141 PY - 2015///1204 KW - Cytokines KW - immunology KW - Female KW - Humans KW - Janus Kinases KW - antagonists & inhibitors KW - Male KW - Myeloproliferative Disorders KW - drug therapy KW - Nitriles KW - Protein Kinase Inhibitors KW - administration & dosage KW - Pyrazoles KW - Pyrimidines KW - Pyrrolidines KW - Sulfonamides KW - T-Lymphocytes, Regulatory KW - enzymology KW - Th17 Cells KW - Time Factors KW - Tumor Cells, Cultured N1 - Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1111/bjh.13519 ER -