TY - GEN AU - Liu,Tao AU - Ma,Ming AU - Ge,Hui-Ming AU - Yang,Chunying AU - Cleveland,John AU - Shen,Ben TI - Synthesis and evaluation of 8,4'-dideshydroxy-leinamycin revealing new insights into the structure-activity relationship of the anticancer natural product leinamycin SN - 1464-3405 PY - 2016///0620 KW - Antibiotics, Antineoplastic KW - chemical synthesis KW - Biological Products KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - Humans KW - Lactams KW - Molecular Conformation KW - Streptomyces KW - chemistry KW - Structure-Activity Relationship KW - Thiazoles N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.bmcl.2015.05.078 ER -