TY - GEN AU - Schmidt,Susanne AU - Bohn-Wippert,Kathrin AU - Schlattmann,Peter AU - Zell,Roland AU - Sauerbrei,Andreas TI - Sequence Analysis of Herpes Simplex Virus 1 Thymidine Kinase and DNA Polymerase Genes from over 300 Clinical Isolates from 1973 to 2014 Finds Novel Mutations That May Be Relevant for Development of Antiviral Resistance SN - 1098-6596 PY - 2016///0414 KW - Acyclovir KW - therapeutic use KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Antiviral Agents KW - Child KW - Child, Preschool KW - DNA-Directed DNA Polymerase KW - genetics KW - Drug Resistance, Viral KW - Female KW - Foscarnet KW - Genotype KW - Herpes Simplex KW - drug therapy KW - Herpesvirus 1, Human KW - drug effects KW - Humans KW - Infant KW - Infant, Newborn KW - Male KW - Middle Aged KW - Mutation KW - Polymorphism, Genetic KW - Retrospective Studies KW - Sequence Analysis, DNA KW - methods KW - Thymidine Kinase KW - Viral Proteins KW - Young Adult N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/AAC.00977-15 ER -