TY - GEN AU - Li,Yi AU - Yang,Jie AU - Chen,Mei-Hong AU - Wang,Qiang AU - Qin,Min-Jian AU - Zhang,Tong AU - Chen,Xiao-Qing AU - Liu,Bao-Lin AU - Wen,Xiao-Dong TI - Ilexgenin A inhibits endoplasmic reticulum stress and ameliorates endothelial dysfunction via suppression of TXNIP/NLRP3 inflammasome activation in an AMPK dependent manner SN - 1096-1186 PY - 2016///0621 KW - AMP-Activated Protein Kinases KW - deficiency KW - Animals KW - Aorta, Thoracic KW - drug effects KW - Apoptosis KW - Cardiovascular Diseases KW - drug therapy KW - Carrier Proteins KW - metabolism KW - Caspase 3 KW - Cell Line KW - Drugs, Chinese Herbal KW - pharmacology KW - Endoplasmic Reticulum Stress KW - Endothelial Cells KW - cytology KW - Gene Knockdown Techniques KW - Humans KW - Ilex KW - Inflammasomes KW - Lipid Metabolism KW - Male KW - Mice KW - Mice, Inbred ICR KW - Mitochondria KW - Rats KW - Rats, Sprague-Dawley KW - Reactive Oxygen Species KW - Thioredoxins KW - Triterpenes N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.phrs.2015.05.012 ER -