Christner, Susan M <br/><br/>
In vitro cytotoxicity and in vivo efficacy, pharmacokinetics, and metabolism of pyrazole-based small molecule inhibitors of Mdm2/4-p53 interaction.  [electronic resource] 

 -  Cancer chemotherapy and pharmacology  Aug 2015 
 - 287-99 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1432-0843 
<br/><br/><label>Standard No.: </label>10.1007/s00280-015-2791-y  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemistry<br/>Drug Screening Assays, Antitumor<br/>Female<br/>HCT116 Cells<br/>Heterografts<br/>Humans<br/>Mice, SCID<br/>Neoplasm Transplantation<br/>Proto-Oncogene Proteins--metabolism<br/>Proto-Oncogene Proteins c-mdm2--metabolism<br/>Pyrazoles--chemistry<br/>Tumor Suppressor Protein p53--metabolism<br/>Ubiquitin-Protein Ligases--metabolism