TY - GEN AU - Kang,Shin-Ae AU - Tsolmon,Bilegtsaikhan AU - Mann,Aman P AU - Zheng,Wei AU - Zhao,Lichao AU - Zhao,Yan Daniel AU - Volk,David E AU - Lokesh,Ganesh L-R AU - Morris,Lynsie AU - Gupta,Vineet AU - Razaq,Wajeeha AU - Rui,Hallgeir AU - Suh,K Stephen AU - Gorenstein,David G AU - Tanaka,Takemi TI - Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice SN - 1096-0333 PY - 2015///0914 KW - Alanine Transaminase KW - blood KW - Animals KW - Antineoplastic Agents KW - administration & dosage KW - Aptamers, Nucleotide KW - Aspartate Aminotransferases KW - Biomarkers KW - Chemical and Drug Induced Liver Injury KW - Complement C3a KW - metabolism KW - Complement C5a KW - Cytokines KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - E-Selectin KW - drug effects KW - Female KW - Injections, Intravenous KW - Kidney KW - Liver KW - Male KW - Mice, Inbred ICR KW - Necrosis KW - Risk Assessment N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1016/j.taap.2015.05.011 ER -