Sharma, Ankur <br/><br/>
A novel Monoclonal Antibody against Notch1 Targets Leukemia-associated Mutant Notch1 and Depletes Therapy Resistant Cancer Stem Cells in Solid Tumors.  [electronic resource] 

 -  Scientific reports  Jun 2015 
 - 11012 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2045-2322 
<br/><br/><label>Standard No.: </label>10.1038/srep11012  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies, Monoclonal--pharmacology<br/>Antibody Affinity<br/>Antineoplastic Agents--pharmacology<br/>Doxorubicin--pharmacology<br/>Drug Resistance, Neoplasm<br/>Drug Synergism<br/>Female<br/>HEK293 Cells<br/>Humans<br/>Mice, Nude<br/>Mutation<br/>Neoplastic Stem Cells--drug effects<br/>Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--drug therapy<br/>Receptor, Notch1--antagonists & inhibitors<br/>Tumor Burden--drug effects<br/>Xenograft Model Antitumor Assays