Prinz, Christian

Organometallic nucleosides induce non-classical leukemic cell death that is mitochondrial-ROS dependent and facilitated by TCL1-oncogene burden. [electronic resource] - Molecular cancer Jun 2015 - 114 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-4598

10.1186/s12943-015-0378-1 doi


Apoptosis--drug effects
Autophagy--drug effects
Caspase 3--metabolism
Cell Line, Tumor
Energy Metabolism--drug effects
Homeostasis--drug effects
Humans
Leukemia, Lymphocytic, Chronic, B-Cell--pathology
Membrane Potential, Mitochondrial--drug effects
Mitochondria--drug effects
Necrosis
Nucleosides--chemistry
Oncogenes
Organometallic Compounds--chemistry
Proto-Oncogene Proteins--genetics
Reactive Oxygen Species--metabolism
Risk Factors
Stromal Cells--drug effects
Tumor Suppressor Protein p53--metabolism