Harrison, Ian F <br/><br/>
Neurorestoration induced by the HDAC inhibitor sodium valproate in the lactacystin model of Parkinson's is associated with histone acetylation and up-regulation of neurotrophic factors.  [electronic resource] 

 -  British journal of pharmacology  Aug 2015 
 - 4200-15 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5381 
<br/><br/><label>Standard No.: </label>10.1111/bph.13208  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetylation<br/>Acetylcysteine--analogs & derivatives<br/>Animals<br/>Behavior, Animal--drug effects<br/>Brain--drug effects<br/>Brain-Derived Neurotrophic Factor--genetics<br/>Disease Models, Animal<br/>Dopaminergic Neurons--drug effects<br/>Glial Cell Line-Derived Neurotrophic Factor--genetics<br/>Histone Deacetylase Inhibitors--pharmacology<br/>Histones--metabolism<br/>Male<br/>Neuroprotective Agents--pharmacology<br/>Parkinson Disease--drug therapy<br/>Proto-Oncogene Proteins c-bcl-2--genetics<br/>Rats, Sprague-Dawley<br/>Up-Regulation<br/>Valproic Acid--pharmacology