TY - GEN AU - Gong,Eun-Yeung AU - Smits,Veronique A J AU - Fumagallo,Felipe AU - Piscitello,Desiree AU - Morrice,Nick AU - Freire,Raimundo AU - Gillespie,David A TI - KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage SN - 2045-2322 PY - 2016///0324 KW - Amino Acid Sequence KW - Catalysis KW - Cell Proliferation KW - Checkpoint Kinase 1 KW - DNA Damage KW - Enzyme Activation KW - G2 Phase Cell Cycle Checkpoints KW - genetics KW - Humans KW - Models, Biological KW - Molecular Sequence Data KW - Mutation KW - Phosphorylation KW - Protein Interaction Domains and Motifs KW - Protein Kinases KW - chemistry KW - Son of Sevenless Proteins N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/srep10856 ER -