TY  - GEN
AU  - Winneroski,Leonard L
AU  - Schiffler,Matthew A
AU  - Erickson,Jon A
AU  - May,Patrick C
AU  - Monk,Scott A
AU  - Timm,David E
AU  - Audia,James E
AU  - Beck,James P
AU  - Boggs,Leonard N
AU  - Borders,Anthony R
AU  - Boyer,Robert D
AU  - Brier,Richard A
AU  - Hudziak,Kevin J
AU  - Klimkowski,Valentine J
AU  - Garcia Losada,Pablo
AU  - Mathes,Brian M
AU  - Stout,Stephanie L
AU  - Watson,Brian M
AU  - Mergott,Dustin J
TI  - Preparation and biological evaluation of conformationally constrained BACE1 inhibitors
SN  - 1464-3391
PY  - 2016///0226
KW  - Amyloid Precursor Protein Secretases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Aspartic Acid Endopeptidases
KW  - Brain Chemistry
KW  - Bridged Bicyclo Compounds
KW  - chemical synthesis
KW  - Crystallography, X-Ray
KW  - Drug Design
KW  - Humans
KW  - Mice
KW  - Molecular Conformation
KW  - Molecular Docking Simulation
KW  - Protease Inhibitors
KW  - Stereoisomerism
KW  - Thiazines
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1016/j.bmc.2015.04.062
ER  -