TY - GEN AU - Voskoboinik,Ilia AU - Whisstock,James C AU - Trapani,Joseph A TI - Perforin and granzymes: function, dysfunction and human pathology SN - 1474-1741 PY - 2015///0730 KW - Animals KW - Apoptosis KW - immunology KW - Cell Communication KW - Cytosol KW - Endosomes KW - Exocytosis KW - physiology KW - Granzymes KW - chemistry KW - Humans KW - Immune System Diseases KW - genetics KW - Infections KW - Inflammation KW - Killer Cells, Natural KW - Neoplasms KW - Perforin KW - Polymorphism, Genetic KW - Secretory Vesicles KW - T-Lymphocytes, Cytotoxic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Review UR - https://doi.org/10.1038/nri3839 ER -