To, Kenneth K W

Pelitinib (EKB-569) targets the up-regulation of ABCB1 and ABCG2 induced by hyperthermia to eradicate lung cancer. [electronic resource] - British journal of pharmacology Aug 2015 - 4089-106 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1476-5381

10.1111/bph.13189 doi


ATP Binding Cassette Transporter, Subfamily B--genetics
ATP Binding Cassette Transporter, Subfamily G, Member 2
ATP-Binding Cassette Transporters--genetics
Adenosine Triphosphatases--metabolism
Aminoquinolines--pharmacology
Aniline Compounds--pharmacology
Antineoplastic Agents--pharmacology
Cell Line, Tumor
Drug Resistance, Neoplasm--drug effects
ErbB Receptors--antagonists & inhibitors
Humans
Hyperthermia, Induced
Lung Neoplasms--drug therapy
Multidrug Resistance-Associated Proteins--genetics
Neoplasm Proteins--genetics
Protein Kinase Inhibitors--pharmacology
Topotecan--pharmacology
Up-Regulation--drug effects