Clarke, Michael O <br/><br/>
Discovery of β-D-2'-deoxy-2'-α-fluoro-4'-α-cyano-5-aza-7,9-dideaza adenosine as a potent nucleoside inhibitor of respiratory syncytial virus with excellent selectivity over mitochondrial RNA and DNA polymerases.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  Jun 2015 
 - 2484-7 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2015.04.073  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adenosine--chemical synthesis<br/>Antiviral Agents--chemical synthesis<br/>Aza Compounds--chemistry<br/>DNA-Directed DNA Polymerase--chemistry<br/>Drug Evaluation, Preclinical<br/>Nucleic Acid Synthesis Inhibitors--chemical synthesis<br/>RNA--chemistry<br/>RNA, Mitochondrial<br/>RNA-Dependent RNA Polymerase--antagonists & inhibitors<br/>Respiratory Syncytial Viruses--drug effects<br/>Structure-Activity Relationship<br/>Virus Replication--drug effects