Dey, Goutam

Marine lipopeptide Iturin A inhibits Akt mediated GSK3β and FoxO3a signaling and triggers apoptosis in breast cancer. [electronic resource] - Scientific reports May 2015 - 10316 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/srep10316 doi


Animals
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Bacillus megaterium--metabolism
Breast Neoplasms--drug therapy
Cell Line, Tumor
Cell Proliferation--drug effects
Cell Survival--drug effects
Female
Forkhead Box Protein O3
Forkhead Transcription Factors--antagonists & inhibitors
Gene Expression Regulation, Neoplastic
Glycogen Synthase Kinase 3--antagonists & inhibitors
Glycogen Synthase Kinase 3 beta
Humans
MCF-7 Cells
Mice
Mice, Inbred BALB C
Peptides, Cyclic--pharmacology
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Signal Transduction--drug effects
Transplantation, Heterologous
Xenograft Model Antitumor Assays