TY  - GEN
AU  - Ng,Ashley P
AU  - Hu,Yifang
AU  - Metcalf,Donald
AU  - Hyland,Craig D
AU  - Ierino,Helen
AU  - Phipson,Belinda
AU  - Wu,Di
AU  - Baldwin,Tracey M
AU  - Kauppi,Maria
AU  - Kiu,Hiu
AU  - Di Rago,Ladina
AU  - Hilton,Douglas J
AU  - Smyth,Gordon K
AU  - Alexander,Warren S
TI  - Early lineage priming by trisomy of Erg leads to myeloproliferation in a Down syndrome model
SN  - 1553-7404
PY  - 2016///0427
KW  - ADP-ribosyl Cyclase 1
KW  - metabolism
KW  - Alleles
KW  - Animals
KW  - Antigens, CD34
KW  - Cell Lineage
KW  - Cell Proliferation
KW  - Chromosomes, Human, Pair 21
KW  - genetics
KW  - Disease Models, Animal
KW  - Down Syndrome
KW  - Erythroid Cells
KW  - Gene Expression Profiling
KW  - Gene Expression Regulation
KW  - Genotype
KW  - Hematopoiesis
KW  - Hematopoietic System
KW  - cytology
KW  - Humans
KW  - Megakaryocytes
KW  - Mice
KW  - Mice, Knockout
KW  - Microarray Analysis
KW  - Oncogene Proteins
KW  - Proto-Oncogene Proteins c-ets
KW  - Sequence Analysis, RNA
KW  - Stem Cells
KW  - Trans-Activators
KW  - Transcription Factors
KW  - Transcriptional Regulator ERG
KW  - Transcriptome
KW  - Trisomy
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1371/journal.pgen.1005211
ER  -