TY  - GEN
AU  - Carrillo,Alexia M
AU  - Hicks,Mellissa
AU  - Khabele,Dineo
AU  - Eischen,Christine M
TI  - Pharmacologically Increasing Mdm2 Inhibits DNA Repair and Cooperates with Genotoxic Agents to Kill p53-Inactivated Ovarian Cancer Cells
SN  - 1557-3125
PY  - 2016///0606
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - therapeutic use
KW  - Apoptosis
KW  - Cell Line, Tumor
KW  - Cell Proliferation
KW  - Cisplatin
KW  - administration & dosage
KW  - Comet Assay
KW  - DNA Breaks, Double-Stranded
KW  - drug effects
KW  - DNA Damage
KW  - DNA Repair
KW  - Etoposide
KW  - Female
KW  - Fibroblasts
KW  - metabolism
KW  - HEK293 Cells
KW  - Humans
KW  - Imidazoles
KW  - Mice
KW  - Mice, Transgenic
KW  - Mutagens
KW  - Ovarian Neoplasms
KW  - genetics
KW  - Piperazines
KW  - Proto-Oncogene Proteins c-mdm2
KW  - Tumor Suppressor Protein p53
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural
UR  - https://doi.org/10.1158/1541-7786.MCR-15-0089
ER  -