TY  - GEN
AU  - Sadowski,Samira M
AU  - Boufraqech,Myriem
AU  - Zhang,Lisa
AU  - Mehta,Amit
AU  - Kapur,Payal
AU  - Zhang,Yaqin
AU  - Li,Zhuyin
AU  - Shen,Min
AU  - Kebebew,Electron
TI  - Torin2 targets dysregulated pathways in anaplastic thyroid cancer and inhibits tumor growth and metastasis
SN  - 1949-2553
PY  - 2016///0524
KW  - Adaptor Proteins, Signal Transducing
KW  - metabolism
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Apoptosis
KW  - drug effects
KW  - Caspases
KW  - Cell Cycle Proteins
KW  - Cell Line, Tumor
KW  - Cell Movement
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - G1 Phase Cell Cycle Checkpoints
KW  - High-Throughput Screening Assays
KW  - Humans
KW  - Inhibitor of Apoptosis Proteins
KW  - Mice, Inbred NOD
KW  - Molecular Targeted Therapy
KW  - Naphthyridines
KW  - Neoplasm Invasiveness
KW  - Phosphoproteins
KW  - Phosphorylation
KW  - Protein Kinase Inhibitors
KW  - Proto-Oncogene Proteins c-akt
KW  - Ribosomal Protein S6 Kinases, 70-kDa
KW  - Signal Transduction
KW  - Survivin
KW  - TOR Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Thyroid Carcinoma, Anaplastic
KW  - drug therapy
KW  - Thyroid Neoplasms
KW  - Time Factors
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Intramural
UR  - https://doi.org/10.18632/oncotarget.3833
ER  -