TY - GEN AU - Kazim,Sabiha AU - Malafa,Mokenge P AU - Coppola,Domenico AU - Husain,Kazim AU - Zibadi,Sherma AU - Kashyap,Trinayan AU - Crochiere,Marsha AU - Landesman,Yosef AU - Rashal,Tami AU - Sullivan,Daniel M AU - Mahipal,Amit TI - Selective Nuclear Export Inhibitor KPT-330 Enhances the Antitumor Activity of Gemcitabine in Human Pancreatic Cancer SN - 1538-8514 PY - 2016///0510 KW - Active Transport, Cell Nucleus KW - drug effects KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - Apoptosis KW - Blotting, Western KW - Cell Adhesion KW - Cell Line, Tumor KW - Cell Proliferation KW - Cell Survival KW - Cyclin-Dependent Kinase Inhibitor p27 KW - metabolism KW - Deoxycytidine KW - administration & dosage KW - Dose-Response Relationship, Drug KW - Drug Synergism KW - Female KW - Humans KW - Hydrazines KW - Mice, Nude KW - Microscopy, Confocal KW - Pancreatic Neoplasms KW - drug therapy KW - Triazoles KW - Tumor Burden KW - Xenograft Model Antitumor Assays KW - Gemcitabine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1535-7163.MCT-15-0104 ER -