TY - GEN AU - Garcia-Manero,Guillermo AU - Tibes,Raoul AU - Kadia,Tapan AU - Kantarjian,Hagop AU - Arellano,Martha AU - Knight,Emily A AU - Xiong,Hao AU - Qin,Qin AU - Munasinghe,Wijith AU - Roberts-Rapp,Lisa AU - Ansell,Peter AU - Albert,Daniel H AU - Oliver,Brian AU - McKee,Mark D AU - Ricker,Justin L AU - Khoury,Hanna Jean TI - Phase 1 dose escalation trial of ilorasertib, a dual Aurora/VEGF receptor kinase inhibitor, in patients with hematologic malignancies SN - 1573-0646 PY - 2016///0512 KW - Aged KW - Aminopyridines KW - adverse effects KW - Antineoplastic Agents KW - Antineoplastic Combined Chemotherapy Protocols KW - Aurora Kinases KW - antagonists & inhibitors KW - Azacitidine KW - Female KW - Hematologic Neoplasms KW - drug therapy KW - Humans KW - Male KW - Maximum Tolerated Dose KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Receptors, Vascular Endothelial Growth Factor N1 - Publication Type: Clinical Trial, Phase I; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s10637-015-0242-6 ER -