TY - GEN AU - Yao,X-Q AU - Jiao,S-S AU - Saadipour,K AU - Zeng,F AU - Wang,Q-H AU - Zhu,C AU - Shen,L-L AU - Zeng,G-H AU - Liang,C-R AU - Wang,J AU - Liu,Y-H AU - Hou,H-Y AU - Xu,X AU - Su,Y-P AU - Fan,X-T AU - Xiao,H-L AU - Lue,L-F AU - Zeng,Y-Q AU - Giunta,B AU - Zhong,J-H AU - Walker,D G AU - Zhou,H-D AU - Tan,J AU - Zhou,X-F AU - Wang,Y-J TI - p75NTR ectodomain is a physiological neuroprotective molecule against amyloid-beta toxicity in the brain of Alzheimer's disease SN - 1476-5578 PY - 2016///0802 KW - ADAM Proteins KW - metabolism KW - ADAM17 Protein KW - Age Factors KW - Alzheimer Disease KW - complications KW - Amyloid beta-Peptides KW - Amyloid beta-Protein Precursor KW - genetics KW - Animals KW - Apoptosis KW - physiology KW - Brain KW - drug effects KW - Case-Control Studies KW - Cognition Disorders KW - etiology KW - Disease Models, Animal KW - Down-Regulation KW - Humans KW - Maze Learning KW - Mice KW - Mice, Transgenic KW - Mutation KW - Nerve Tissue Proteins KW - chemistry KW - Presenilin-1 KW - Protein Structure, Tertiary KW - Receptors, Nerve Growth Factor KW - Recombinant Proteins KW - therapeutic use KW - Transduction, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/mp.2015.49 ER -