TY  - GEN
AU  - Hiraoka,Kiriko
AU  - Inoue,Takahiro
AU  - Taylor,Rhys Dylan
AU  - Watanabe,Takayoshi
AU  - Koshikawa,Nobuko
AU  - Yoda,Hiroyuki
AU  - Shinohara,Ken-ichi
AU  - Takatori,Atsushi
AU  - Sugimoto,Hirokazu
AU  - Maru,Yoshiaki
AU  - Denda,Tadamichi
AU  - Fujiwara,Kyoko
AU  - Balmain,Allan
AU  - Ozaki,Toshinori
AU  - Bando,Toshikazu
AU  - Sugiyama,Hiroshi
AU  - Nagase,Hiroki
TI  - Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate
SN  - 2041-1723
PY  - 2016///0315
KW  - Animals
KW  - Antineoplastic Agents
KW  - chemical synthesis
KW  - Apoptosis
KW  - drug effects
KW  - Caco-2 Cells
KW  - Cellular Senescence
KW  - DNA Damage
KW  - Drug Evaluation, Preclinical
KW  - Female
KW  - HT29 Cells
KW  - Humans
KW  - Imidazoles
KW  - Mice, Nude
KW  - Mutation
KW  - Neoplasms, Experimental
KW  - drug therapy
KW  - Nylons
KW  - Proto-Oncogene Proteins p21(ras)
KW  - antagonists & inhibitors
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/ncomms7706
ER  -