Hiraoka, Kiriko <br/><br/>
Inhibition of KRAS codon 12 mutants using a novel DNA-alkylating pyrrole-imidazole polyamide conjugate.  [electronic resource] 

 -  Nature communications  Apr 2015 
 - 6706 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>2041-1723 
<br/><br/><label>Standard No.: </label>10.1038/ncomms7706  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Apoptosis--drug effects<br/>Caco-2 Cells<br/>Cellular Senescence--drug effects<br/>DNA Damage<br/>Drug Evaluation, Preclinical<br/>Female<br/>HT29 Cells<br/>Humans<br/>Imidazoles--chemical synthesis<br/>Mice, Nude<br/>Mutation<br/>Neoplasms, Experimental--drug therapy<br/>Nylons--chemical synthesis<br/>Proto-Oncogene Proteins p21(ras)--antagonists & inhibitors