Nandakumar, Satish K

Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice. [electronic resource] - Experimental hematology Jul 2015 - 565-77.e1-10 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1873-2399

10.1016/j.exphem.2015.04.002 doi


Animals
B-Lymphocytes--pathology
Bone Marrow Cells--metabolism
Cell Division
Cell Nucleus--metabolism
Cell Transformation, Neoplastic--genetics
Cells, Cultured
Colony-Forming Units Assay
GATA2 Transcription Factor--genetics
Gene Expression Regulation, Leukemic--drug effects
Genes, Synthetic
Genes, myc
Hematopoietic Stem Cells--cytology
Homeodomain Proteins--genetics
Humans
Leukemia, Myeloid, Acute--genetics
Lymphopoiesis--genetics
Mice
Mice, Inbred C57BL
Mice, Transgenic
Mutation
Myeloid Cells--metabolism
Myelopoiesis--genetics
Receptors, Estrogen--genetics
Recombinant Fusion Proteins--metabolism
T-Lymphocytes--pathology
Tamoxifen--pharmacology