TY  - GEN
AU  - Shaffer,Christopher L
AU  - Patel,Nandini C
AU  - Schwarz,Jacob
AU  - Scialis,Renato J
AU  - Wei,Yunjing
AU  - Hou,Xinjun J
AU  - Xie,Longfei
AU  - Karki,Kapil
AU  - Bryce,Dianne K
AU  - Osgood,Sarah M
AU  - Hoffmann,William E
AU  - Lazzaro,John T
AU  - Chang,Cheng
AU  - McGinnis,Dina F
AU  - Lotarski,Susan M
AU  - Liu,JianHua
AU  - Obach,R Scott
AU  - Weber,Mark L
AU  - Chen,Laigao
AU  - Zasadny,Kenneth R
AU  - Seymour,Patricia A
AU  - Schmidt,Christopher J
AU  - Hajós,Mihály
AU  - Hurst,Raymond S
AU  - Pandit,Jayvardhan
AU  - O'Donnell,Christopher J
TI  - The discovery and characterization of the α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor potentiator N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide (PF-04958242)
SN  - 1520-4804
PY  - 2015///0904
KW  - Administration, Oral
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Animals
KW  - Binding Sites
KW  - Disease Models, Animal
KW  - Dogs
KW  - Dose-Response Relationship, Drug
KW  - Drug Discovery
KW  - Drug Evaluation, Preclinical
KW  - methods
KW  - Drug Stability
KW  - Female
KW  - Humans
KW  - Male
KW  - Memory, Short-Term
KW  - drug effects
KW  - Mice, Inbred C57BL
KW  - Middle Aged
KW  - Protein Conformation
KW  - Rats, Sprague-Dawley
KW  - Receptors, AMPA
KW  - metabolism
KW  - Schizophrenia
KW  - drug therapy
KW  - Structure-Activity Relationship
KW  - Sulfonamides
KW  - chemistry
KW  - Thiophenes
KW  - Young Adult
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1021/acs.jmedchem.5b00300
ER  -