TY  - GEN
AU  - Kümler,Iben
AU  - Balslev,Eva
AU  - Stenvang,Jan
AU  - Brünner,Nils
AU  - Nielsen,Dorte
TI  - A phase II study of weekly irinotecan in patients with locally advanced or metastatic HER2- negative breast cancer and increased copy numbers of the topoisomerase 1 (TOP1) gene: a study protocol
SN  - 1471-2407
PY  - 2016///0108
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Camptothecin
KW  - administration & dosage
KW  - DNA Topoisomerases, Type I
KW  - genetics
KW  - Drug Administration Schedule
KW  - Female
KW  - Gene Dosage
KW  - Genetic Markers
KW  - Humans
KW  - Irinotecan
KW  - Neoplasm Metastasis
KW  - Prospective Studies
KW  - Receptor, ErbB-2
KW  - Topoisomerase I Inhibitors
KW  - Treatment Outcome
N1  - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s12885-015-1072-9
ER  -