TY  - GEN
AU  - Ayez,Ninos
AU  - van der Stok,Eric P
AU  - de Wilt,Hans
AU  - Radema,Sandra A
AU  - van Hillegersberg,Richard
AU  - Roumen,Rudi M
AU  - Vreugdenhil,Gerard
AU  - Tanis,Pieter J
AU  - Punt,Cornelis J
AU  - Dejong,Cornelis H
AU  - Jansen,Rob L
AU  - Verheul,Henk M
AU  - de Jong,Koert P
AU  - Hospers,Geke A
AU  - Klaase,Joost M
AU  - Legdeur,Marie-Cecile
AU  - van Meerten,Esther
AU  - Eskens,Ferry A
AU  - van der Meer,Nelly
AU  - van der Holt,Bruno
AU  - Verhoef,Cornelis
AU  - Grünhagen,Dirk J
TI  - Neo-adjuvant chemotherapy followed by surgery versus surgery alone in high-risk patients with resectable colorectal liver metastases: the CHARISMA randomized multicenter clinical trial
SN  - 1471-2407
PY  - 2016///0201
KW  - Adult
KW  - Aged
KW  - Colorectal Neoplasms
KW  - drug therapy
KW  - Combined Modality Therapy
KW  - Digestive System Surgical Procedures
KW  - Disease-Free Survival
KW  - Female
KW  - Humans
KW  - Liver Neoplasms
KW  - Male
KW  - Middle Aged
KW  - Neoadjuvant Therapy
KW  - Organoplatinum Compounds
KW  - administration & dosage
KW  - Oxaliplatin
KW  - Risk Factors
N1  - Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1186/s12885-015-1199-8
ER  -