TY - GEN AU - Hao,Liang AU - Chen,Jianwei AU - Zhu,Zheng AU - Reddy,Michael S AU - Mountz,John D AU - Chen,Wei AU - Li,Yi-Ping TI - Odanacatib, A Cathepsin K-Specific Inhibitor, Inhibits Inflammation and Bone Loss Caused by Periodontal Diseases SN - 1943-3670 PY - 2016///1213 KW - Alveolar Bone Loss KW - microbiology KW - Animals KW - Anti-Inflammatory Agents KW - therapeutic use KW - Bacteroidaceae Infections KW - immunology KW - Biphenyl Compounds KW - Cathepsin K KW - antagonists & inhibitors KW - Disease Models, Animal KW - Epithelial Cells KW - drug effects KW - Female KW - Gingiva KW - Gram-Negative Bacterial Infections KW - Immunity, Innate KW - Macrophages KW - Male KW - Mice KW - Mice, Inbred BALB C KW - Mice, Inbred Strains KW - Osteoclasts KW - Periodontitis KW - Porphyromonas gingivalis KW - T-Lymphocytes KW - Tannerella forsythia KW - Toll-Like Receptor 4 KW - Toll-Like Receptor 5 KW - Toll-Like Receptor 9 KW - Treponema denticola KW - Treponemal Infections N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1902/jop.2015.140643 ER -