Lozano-Santos, Carol

Arsenic trioxide synergistically potentiates the cytotoxic effect of fludarabine in chronic lymphocytic leukemia cells by further inactivating the Akt and ERK signaling pathways. [electronic resource] - Biochemical and biophysical research communications May 2015 - 243-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2015.04.007 doi


Adult
Aged
Antineoplastic Agents--pharmacology
Apoptosis--drug effects
Arsenic Trioxide
Arsenicals--pharmacology
Drug Synergism
Enzyme Inhibitors--pharmacology
Female
Growth Inhibitors--pharmacology
Humans
Leukemia, Lymphocytic, Chronic, B-Cell--drug therapy
MAP Kinase Signaling System--drug effects
Male
Middle Aged
Oxides--pharmacology
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Signal Transduction--drug effects
Tumor Cells, Cultured
Vidarabine--analogs & derivatives