Sehgal, Alfica

An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia. [electronic resource] - Nature medicine May 2015 - 492-7 p. digital

Publication Type: Journal Article

1546-170X

10.1038/nm.3847 doi


Animals
Antithrombins--chemistry
Blood Coagulation--drug effects
Dose-Response Relationship, Drug
Factor IX--chemistry
Factor VIII--chemistry
Female
Hemophilia A--drug therapy
Hemostasis--drug effects
Homozygote
Humans
Male
Mice
Mutation
RNA Interference