TY - GEN AU - Oruqaj,Gani AU - Karnati,Srikanth AU - Vijayan,Vijith AU - Kotarkonda,Lakshmi Kanth AU - Boateng,Eistine AU - Zhang,Wenming AU - Ruppert,Clemens AU - Günther,Andreas AU - Shi,Wei AU - Baumgart-Vogt,Eveline TI - Compromised peroxisomes in idiopathic pulmonary fibrosis, a vicious cycle inducing a higher fibrotic response via TGF-β signaling SN - 1091-6490 PY - 2015///0629 KW - Animals KW - Collagen Type I KW - metabolism KW - Disease Models, Animal KW - Down-Regulation KW - Female KW - Fibroblasts KW - Gene Knockdown Techniques KW - Humans KW - Idiopathic Pulmonary Fibrosis KW - Inflammation Mediators KW - Interleukin-6 KW - Lipid Metabolism KW - Lung KW - pathology KW - Male KW - Membrane Proteins KW - Mice, Inbred C57BL KW - Middle Aged KW - Models, Biological KW - Oxidation-Reduction KW - PPAR alpha KW - agonists KW - Peroxisomes KW - RNA, Small Interfering KW - Reactive Oxygen Species KW - Signal Transduction KW - Smad Proteins KW - Transcription Factor AP-1 KW - Transforming Growth Factor beta KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article UR - https://doi.org/10.1073/pnas.1415111112 ER -