Molecular tweezers inhibit islet amyloid polypeptide assembly and toxicity by a new mechanism. [electronic resource]
- ACS chemical biology Jun 2015
- 1555-69 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1554-8937
10.1021/acschembio.5b00146 doi
Animals Bridged-Ring Compounds--chemistry Cell Line Cell Survival--drug effects Humans Hypoglycemic Agents--chemistry Insulin-Secreting Cells--cytology Islet Amyloid Polypeptide--antagonists & inhibitors Models, Molecular Organophosphates--chemistry Protein Aggregates--drug effects Protein Binding Protein Structure, Secondary Protein Structure, Tertiary Rats