Duluc, Camille <br/><br/>
Pharmacological targeting of the protein synthesis mTOR/4E-BP1 pathway in cancer-associated fibroblasts abrogates pancreatic tumour chemoresistance.  [electronic resource] 

 -  EMBO molecular medicine  Jun 2015 
 - 735-53 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1757-4684 
<br/><br/><label>Standard No.: </label>10.15252/emmm.201404346  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--antagonists & inhibitors<br/>Adenocarcinoma--drug therapy<br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Carcinoma, Pancreatic Ductal--drug therapy<br/>Cell Cycle Proteins<br/>Cells, Cultured<br/>Deoxycytidine--analogs & derivatives<br/>Disease Models, Animal<br/>Drug Resistance<br/>Fibroblasts--metabolism<br/>Heterografts<br/>Humans<br/>Mice, Nude<br/>Phosphoproteins--antagonists & inhibitors<br/>Somatostatin--analogs & derivatives<br/>TOR Serine-Threonine Kinases--antagonists & inhibitors<br/>Treatment Outcome<br/>Gemcitabine